Recovery in Untrained Spinalized Cats Neurotrophic Factors Promote and Enhance Locomotor
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منابع مشابه
Neurotrophic factors promote and enhance locomotor recovery in untrained spinalized cats.
In spinal cats, locomotor recovery without rehabilitation is limited, but weight-bearing stepping returns with treadmill training. We studied whether neurotrophins administered to the injury site also restores locomotion in untrained spinal cats and whether combining both neurotrophins and training further improves recovery. Ordinary rat fibroblasts or a mixture of fibroblasts secreting brain-d...
متن کاملCould neurotrophins replace treadmill training as locomotor therapy following spinal cord injury? Focus on "neurotrophic factors promote and enhance locomotor recovery in untrained spinalized cats".
How to repair the injured spinal cord is a question that scientists have struggled with for decades. The answer is of course still a mystery. But ask people on the street for their opinion and they will likely offer something like “stem cells” as the solution. I find it amusing (and honestly, a bit annoying) that family and friends continue to ask me if there is anything new with stem cells. My...
متن کاملCould Neurotrophins Replace Treadmill Training as Locomotor Therapy Following Spinal Cord Injury? Focus on “Neurotrophic Factors Promote and Enhance Locomotor Recovery in Untrained Spinalized Cats”
How to repair the injured spinal cord is a question that scientists have struggled with for decades. The answer is of course still a mystery. But ask people on the street for their opinion and they will likely offer something like “stem cells” as the solution. I find it amusing (and honestly, a bit annoying) that family and friends continue to ask me if there is anything new with stem cells. My...
متن کاملMinocycline Enhance Restorative Ability of Olfactory Ensheathing Cells by Upregulation of BDNF and GDNF Expression After Spinal Cord Injury
Purpose: Spinal cord injury is a global public health issue that results in extensive neuronal degeneration, axonal and myelin loss and severe functional deficits. Neurotrophic factors are potential treatment for reducing secondary damage, promoting axon growth, and are responsible for inducing myelination after injury. Olfactory ensheathing cells (OECs) and minocycline have been shown to promo...
متن کاملTreadmill training promotes spinal changes leading to locomotor recovery after partial spinal cord injury in cats.
After a spinal hemisection at thoracic level in cats, the paretic hindlimb progressively recovers locomotion without treadmill training but asymmetries between hindlimbs persist for several weeks and can be seen even after a further complete spinal transection at T13. To promote optimal locomotor recovery after hemisection, such asymmetrical changes need to be corrected. In the present study we...
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تاریخ انتشار 2007